Terbutaline

Indications:
Bronchodilator and Tocolytic; Used in asthma, bronchitis, and emphysema; Also used in premature labour

Dosage:
Adult – 1.25 to 5 mg (maximum 15 mg daily) in divided doses
Paediatric – 2.5 mg orally every 6 to 8 hours (maximum 7.5 mg daily)

Mechanism of Action:
Stimulation through beta-adrenergic receptors of intracellular adenyl cyclase. This leads to relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells

Side Effects:
Shakiness in the legs, arms, hands, or feet; trembling or shaking of the hands or feet

Molecular Structure:
TERBUTALINE

Reference:
Pharmacology & Pharmacotherapeutics – 24th Edition, R.S. Sartoskar
www.reference.medscape.com
www.drugs.com/drug_information.html

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