Simethicone

Indications:
Antiflatulent; mainly used to reduce gas from the gastrointestinal tract (GIT)

Dosage:
Adult – 40 to 125 mg orally after meals, not to exceed 500 mg/24 hours
Paediatric – 40 mg orally 4 times a day

Mechanism of Action:
Decreases the surface tension of gas bubbles thereby disperses and prevents gas pockets in the GI system

Side Effects:
Mild diarrhoea, nausea and vomiting

Molecular Structure:
SIMETHICONE

Reference:
Pharmacology & Pharmacotherapeutics – 24th Edition, R.S. Sartoskar
www.reference.medscape.com
www.drugs.com/drug_information.html

Note: This information is intended for doctors and students of medicine. Every effort has been made to provide actual information, especially on medicine dosage, however, it is advisable that doctors make final decisions on their usage. This information is not meant to replace a proper medical diagnosis or therapy. Responsibility taken by authors is suitable for this kind of publication and is not tantamount to responsibility for an individual medical advice.
The authors, consultants and publishers of this information do not take any responsibility for possible mistakes or harms resulted from the information usage. Any cases of legal claims connected with medicines and chemical substances being under clinical examination are not going to be taken into consideration
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