Indications:
Analgesic and Antipyretic; Used in headache, muscle aches, arthritis, backache, toothaches, colds, and fevers; Lacks anti-inflammatory, antiplatelet, and gastric ulcerative effects
Dosage:
Adult – 1 to 4 gm daily in divided doses
Paediatric – 75 mg/kg in 24 hours; not to exceed 3750 mg
Mechanism of Action:
Acts primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase enzymes involved in prostaglandin synthesis
Side Effects:
Nausea, vomiting, constipation
Molecular Structure:
Reference:
Pharmacology & Pharmacotherapeutics – 24th Edition, R.S. Sartoskar
www.reference.medscape.com
www.drugs.com/drug_information.html
Note: This information is intended for doctors and students of medicine. Every effort has been made to provide actual information, especially on medicine dosage, however, it is advisable that doctors make final decisions on their usage. This information is not meant to replace a proper medical diagnosis or therapy. Responsibility taken by authors is suitable for this kind of publication and is not tantamount to responsibility for an individual medical advice.
The authors, consultants and publishers of this information do not take any responsibility for possible mistakes or harms resulted from the information usage. Any cases of legal claims connected with medicines and chemical substances being under clinical examination are not going to be taken into consideration
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