Gentamicin

Indications:
Antibiotic; Effective in bacterial neonatal sepsis; bacterial septicemia; and serious bacterial infections of the central nervous system (meningitis), urinary tract, respiratory tract, gastrointestinal tract (including peritonitis), skin, bone and soft tissue (including burns)

Dosage:
Adult – 5 mg/Kg over 30 to 60 minutes by IV route
Paediatric – 3 mg/Kg over 30 to 60 minutes by IV route

Mechanism of Action:
As an aminoglycoside, it binds to the prokaryotic ribosome, inhibiting protein synthesis in susceptible bacteria

Side Effects:
Nausea, vomiting, stomach upset, loss of appetite, and injection site reactions

Molecular Structure:

Reference:
Pharmacology & Pharmacotherapeutics – 24^th Edition, R.S. Sartoskar
www.reference.medscape.com
www.drugs.com/drug_information.html

Note: This information is intended for doctors and students of medicine. Every effort has been made to provide actual information, especially on medicine dosage, however, it is advisable that doctors make final decisions on their usage. This information is not meant to replace a proper medical diagnosis or therapy. Responsibility taken by authors is suitable for this kind of publication and is not tantamount to responsibility for an individual medical advice.

The authors, consultants and publishers of this information do not take any responsibility for possible mistakes or harms resulted from the information usage. Any cases of legal claims connected with medicines and chemical substances being under clinical examination are not going to be taken into consideration

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